Mouse Monoclonal anti-Cavß4 Antibody

Item#:

xAP-0014

Size	Price	Quantity
100.0 ug	$400.00

please find our citations on google scholar

Product Overview

Catalog Number	xAP-0014
ID	Mouse Monoclonal anti-Cavß4 Antibody
Antigen Description	Voltage-dependent L-type calcium channel subunit beta-4 (CavÃ¿4) is a member of the membrane-associated guanylate kinase (GK) protein family and a cytoplasmic subunit of voltage-gated calcium channels. Expressed predominantly in the cerebellum and kidney, it is responsible for calcium entry into nerve termini and subsequent neurotransmitter release via its association with membrane-trafficking protein synaptotagmin 1 (Syt 1). It regulates synaptic transmission, increases the readily releasable pool of synaptic vesicles, and plays a role in synaptic vesicle plasticity and maturation through its association with CavÃ¿1, RIM1, and actin filaments (F-actin). CavÃ¿4 has been linked to psychiatric and anxiety disorders including major depressive disorder (MDD) and schizophrenia and is a potential therapeutic target in their study and treatment.
Size	100ug
Immunogen	Synthetic peptide corresponding to amino acids 458-474 of rat Cavß4
Clone	#N10/7
Antibody Isotype	Mouse IgG1
Host Species	Mouse
Preparation	The antibody was purified by affinity chromatography.
Formulation	The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application	WB
Storage & Handling	Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.

ANGIO-PROTEOMIE, ALL RIGHTS RESERVED