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Novel Coronavirus 2019-nCoV Spike Glycoprotein-S2, Recombinant
Product Name Novel Coronavirus 2019-nCoV Spike Glycoprotein-S2, Recombinant
Synonyms
INTRODUCTION A human infecting coronavirus (viral pneumonia) called 2019 novel coronavirus, 2019-nCoV was found in the fish market at the city of Wuhan, Hubei province of China on December 2019. The 2019-nCoV shares an 87% identity to the 2 bat-derived severe acute respiratory syndrome 2018 SARS-CoV-2 located in Zhoushan of eastern China. 2019-nCoV has an analogous receptor-BD-structure to that of 2018 SARS-CoV, even though there is a.a. diversity so thus the 2019-nCoV might bind to ACE2 receptor protein (angiotensin-converting enzyme 2) in humans. While bats are possibly the host of 2019-nCoV, researchers suspect that animal from the ocean sold at the seafood market was an intermediate host. RSCU analysis proposes that the 2019-nCoV is a recombinant within the viral spike glycoprotein between the bat coronavirus and an unknown coronavirus.
DESCRIPTION The HEK293 derived recombinant protein contains the Novel Coronavirus 2019-nCoV Spike Glycoprotein S2, Wuhan-Hu-1 strain, amino acids 685-1211 fused to Fc tag at C-terminal.
Uniprot Accesion Number
Amino Acid Sequence
Source HEK293.
Physical Appearance and Stability Lyophilized powder and stable for minimum of 1 year after delivery if stored below -20C
Formulation Novel Coronavirus 2019-nCoV Spike Glycoprotein-S2, Recombinant solution is supplied in DPBS before Lyophilization.
Purity Novel Coronavirus 2019-nCoV Spike Glycoprotein-S2, Recombinant is >85% pure as determined SDS-PAGE
Application Each laboratory should determine an optimum working titer for use in its particular application.
Solubility
Biological Activity Reactivity with SARS infected individuals not tested.
Shipping Format and Condition Lyophilized powder at room temperature.
Usage Statement Our products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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