Mouse Monoclonal Antibody to CD191

Item#:

sAP-1725

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-1725
Product Name	Mouse Monoclonal Antibody to CD191
Target Molecle	CD191
Aliases	CCR1; CKR1; CKR-1; HM145; CMKBR1; MIP1aR; SCYAR1
Species	Human;
MW	41.2kDa
Enterez GeneID	1230
General Information	This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p.
Immunogen	Purified recombinant fragment of human CD191 (AA
Clone	MM8E10G6
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1.Dis Markers. 2014;2014