Mouse Monoclonal Antibody to MAP2K3

Item#:

sAP-1313

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-1313
Product Name	Mouse Monoclonal Antibody to MAP2K3
Target Molecle	MAP2K3
Aliases	MEK3; MKK3; MAPKK3; PRKMK3; SAPKK2; SAPKK-2
Species	Human;
MW	39.3kDa
Enterez GeneID	5606
General Information	The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene.;
Immunogen	Purified recombinant fragment of human MAP2K3 (AA
Clone	MM2E12D11;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1.Breast Cancer Res Treat. 2010 Sep;123(2)