Mouse Monoclonal Antibody to MECP2

Item#:

sAP-1242

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-1242
Product Name	Mouse Monoclonal Antibody to MECP2
Target Molecle	MECP2
Aliases	RS; RTS; RTT; PPMX; MRX16; MRX79; MRXSL; AUTSX3; MRXS13
Species	Human;
MW	52.4kDa
Enterez GeneID	4204
General Information	DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.;
Immunogen	Purified recombinant fragment of human MECP2 (AA
Clone	MM8H4A5B9;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1.Cancer Res. 2014 Jun 15;74(12)