Mouse Monoclonal Antibody to MMP14

Item#:

sAP-1206

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-1206
Product Name	Mouse Monoclonal Antibody to MMP14
Target Molecle	MMP14
Aliases	MMP-14; MMP-X1; MT-MMP; MT1MMP; MTMMP1; WNCHRS; MT1-MMP; MT-MMP 1
Species	Human;
MW	65.9kDa
Enterez GeneID	4323
General Information	Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.;
Immunogen	Purified recombinant fragment of human MMP14 (AA
Clone	MM6A11D1;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1.Cancer Res. 2014 Jun 15;74(12)