Mouse Monoclonal Antibody to Notch3

Item#:

sAP-1205

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-1205
Product Name	Mouse Monoclonal Antibody to Notch3
Target Molecle	Notch3
Aliases	IMF2; CASIL; CADASIL
Species	Human;
MW	243.6kDa
Enterez GeneID	4854
General Information	This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).;
Immunogen	Purified recombinant fragment of human Notch3 (AA
Clone	MM2E4D11;
Isotype	Mouse IgG2b
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1.J Virol. 2011 Sep;85(17)