Mouse Monoclonal Antibody to DNMT3B

Item#:

sAP-1192

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-1192
Product Name	Mouse Monoclonal Antibody to DNMT3B
Target Molecle	DNMT3B
Aliases	ICF; ICF1; M.HsaIIIB
Species	Human;
MW	95.8kDa
Enterez GeneID	1789
General Information	CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.;
Immunogen	Purified recombinant fragment of human DNMT3B (AA
Clone	MM7E5E9C1;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1.PLoS One. 2013 Jul 19;8(7)