Home Page > ANTIBODY > MONOCLONAL ANTIBODY > Mouse Monoclonal Antibody >  Mouse Monoclonal Antibody to Rab8

Mouse Monoclonal Antibody to Rab8
Item#:
sAP-1189
Size Price Quantity
50.0 ug $320.00
Catalog Number sAP-1189
Product Name Mouse Monoclonal Antibody to Rab8
Target Molecle Rab8
Aliases MEL; RAB8A
Species Human;
MW 23.7kDa
Enterez GeneID 4218
General Information The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1.;
Immunogen Purified recombinant fragment of human Rab8 (AA
Clone MM7G8B11;
Isotype Mouse IgG2b
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1.J Biol Chem. 2014 Feb 14;289(7)
N
N

ANGIO-PROTEOMIE, ALL RIGHTS RESERVED