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Mouse Monoclonal Antibody to FGFR3
Item#:
sAP-1118
Size Price Quantity
50.0 ug $320.00
Catalog Number sAP-1118
Product Name Mouse Monoclonal Antibody to FGFR3
Target Molecle FGFR3
Aliases ACH; CEK2; JTK4; CD333; HSFGFR3EX
Species Human;
MW 87.7kDa
Enterez GeneID 2261
General Information This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Jul 2009];
Immunogen Purified recombinant fragment of human FGFR3 (AA
Clone MM2H10B4;
Isotype Mouse IgG1
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References PLoS One. 2012;7(9)
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