Mouse Monoclonal Antibody to LDLR

Item#:

sAP-1113

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-1113
Product Name	Mouse Monoclonal Antibody to LDLR
Target Molecle	LDLR
Aliases	FH; FHC; LDLCQ2
Species	Human;
MW	95.4kDa
Enterez GeneID	3949
General Information	The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.
Immunogen	Purified recombinant fragment of human LDLR (AA
Clone	MM7H5B11;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	BMC Cancer. 2013 Nov 4;13