Mouse Monoclonal Antibody to PLCG2

Item#:

sAP-1071

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-1071
Product Name	Mouse Monoclonal Antibody to PLCG2
Target Molecle	PLCG2
Aliases	FCAS3; APLAID; PLC-IV; PLC-gamma-2
Species	Human;
MW	148kDa
Enterez GeneID	5336
General Information	The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.
Immunogen	Synthesized peptide of human PLCG2 (AA
Clone	MM3A8B6;
Isotype	Mouse IgG2b
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Med Oncol. 2012 Jun;29(2)