Mouse Monoclonal Antibody to PKN1

Item#:

sAP-1066

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-1066
Product Name	Mouse Monoclonal Antibody to PKN1
Target Molecle	PKN1
Aliases	DBK; PKN; PAK1; PRK1; PAK-1; PRKCL1; PKN-ALPHA
Species	Human;
MW	104kDa
Enterez GeneID	5585
General Information	The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Immunogen	Purified recombinant fragment of human PKN1 (AA
Clone	MM4H10B1;
Isotype	Mouse IgG2b
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Mol Cell Biol. 2012 Aug;32(15)