Mouse Monoclonal Antibody to TCL1A

Item#:

sAP-1064

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-1064
Product Name	Mouse Monoclonal Antibody to TCL1A
Target Molecle	TCL1A
Aliases	TCL1
Species	Human;
MW	13.5kDa
Enterez GeneID	8115
General Information	Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).
Immunogen	Purified recombinant fragment of human TCL1A (AA
Clone	MM2E3A5;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Cancer. 2011 Sep 1;117(17)