Mouse Monoclonal Antibody to APP

Item#:

sAP-1058

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-1058
Product Name	Mouse Monoclonal Antibody to APP
Target Molecle	APP
Aliases	AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma
Species	Human;
MW	87kDa
Enterez GeneID	351
General Information	This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
Immunogen	Purified recombinant fragment of human APP (AA
Clone	MM5H10A10;
Isotype	Mouse IgG2b
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Cerebrovasc Dis. 2010;29(1)