Mouse Monoclonal Antibody to PIK3CG

Item#:

sAP-1036

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-1036
Product Name	Mouse Monoclonal Antibody to PIK3CG
Target Molecle	PIK3CG
Aliases	PI3K; PIK3; PI3CG; PI3Kgamma; p110gamma; p120-PI3K
Species	Human;
MW	126.5kDa
Enterez GeneID	5294
General Information	This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene.
Immunogen	Purified recombinant fragment of human PIK3CG (AA
Clone	MM4B5D2;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Clin Cancer Res. 2013 Mar 15;19(6)