Mouse Monoclonal Antibody to CD33

Item#:

sAP-1002

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-1002
Product Name	Mouse Monoclonal Antibody to CD33
Target Molecle	CD33
Aliases	p67; SIGLEC3; SIGLEC-3
Species	Human;
MW	39.8kDa
Enterez GeneID	945
General Information	The protein encoded by this gene belongs to putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro) and CD33 plays potential key roles in the pathogenesis of Alzheimer's disease (AD)
Immunogen	Purified recombinant fragment of human CD33 (AA
Clone	MM2C6B7;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. MAbs. 2011 Jan-Feb;3(1)