Mouse Monoclonal Antibody to WHSC2

Item#:

sAP-0992

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0992
Product Name	Mouse Monoclonal Antibody to WHSC2
Target Molecle	WHSC2
Aliases	NELFA; NELF-A; P/OKcl.15
Species	Human;
MW	57.3kDa
Enterez GeneID	7469
General Information	This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation. ; ;
Immunogen	Purified recombinant fragment of human WHSC2 (AA
Clone	MM6B11H8;
Isotype	Mouse IgG2b
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1.Arch Histol Cytol. 1999 Aug;62(3)