Home Page > ANTIBODY > MONOCLONAL ANTIBODY > Mouse Monoclonal Antibody >  Mouse Monoclonal Antibody to C17ORF53

Mouse Monoclonal Antibody to C17ORF53
Item#:
sAP-0966
Size Price Quantity
50.0 ug $320.00
Catalog Number sAP-0966
Product Name Mouse Monoclonal Antibody to C17ORF53
Target Molecle C17ORF53
Aliases
Species Human;
MW 69.8kDa
Enterez GeneID 78995
General Information C17orf53 (chromosome 17 open reading frame 53) is a 647 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17. ; ; ;
Immunogen Purified recombinant fragment of human C17ORF53 (AA
Clone MM7A3A9;
Isotype Mouse IgG2b
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1.J Biol Chem. 2008 Dec 5;283(49)
N
N

ANGIO-PROTEOMIE, ALL RIGHTS RESERVED