Mouse Monoclonal Antibody to ABCB1

Item#:

sAP-0883

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0883
Product Name	Mouse Monoclonal Antibody to ABCB1
Target Molecle	ABCB1
Aliases	CLCS; MDR1; P-GP; PGY1; ABC20; CD243; GP170
Species	Human;
MW	141.5kDa
Enterez GeneID	5243
General Information	The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. ;
Immunogen	Purified recombinant fragment of human ABCB1 (AA
Clone	MM6G11F8;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. J Immunol. 2012 Dec 15;189(12)