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Mouse Monoclonal Antibody to PTPRC
Item#:
sAP-0880
Size Price Quantity
50.0 ug $320.00
Catalog Number sAP-0880
Product Name Mouse Monoclonal Antibody to PTPRC
Target Molecle PTPRC
Aliases LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180
Species Human;
MW 147.3kDa
Enterez GeneID 5788
General Information The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. ; ; ;
Immunogen Purified recombinant fragment of human PTPRC (AA
Clone MM5D3A3;
Isotype Mouse IgG1
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1. Pharmacol Rep. 2012;64(6)
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