Mouse Monoclonal Antibody to TFRC

Item#:

sAP-0855

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0855
Product Name	Mouse Monoclonal Antibody to TFRC
Target Molecle	TFRC
Aliases	T9; TR; TFR; p90; CD71; TFR1; TRFR
Species	Human; Mouse; Monkey; Rat;
MW	85kDa
Enterez GeneID	7037
General Information	Transferrin receptor is a carrier protein for transferrin. It is needed for the import of iron into the cell and is regulated in response to intracellular iron concentration. Low iron concentrations promote increased levels of transferrin receptor, to increase iron intake into the cell. Thus, transferrin receptor maintains cellular iron homeostasis. Expression of human TFR1, but not human TFR2, in hamster cell lines markedly enhanced the infection of viruses pseudotyped with the glycoprotein of Machupo, Guanarito, and Junin viruses, but not with those of Lassa or lymphocytic choriomeningitis viruses. An anti-TFR1 antibody efficiently inhibited the replication of Machupo, Guanarito, Junin, and Sabia viruses, but not that of Lassa virus.TFR1 is a cellular receptor for New World hemorrhagic fever arenaviruses. ; ;
Immunogen	Purified recombinant fragment of human TFRC (AA
Clone	MM1A1B2;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Cancer Lett. 2013 Apr 28;330(2)