Mouse Monoclonal Antibody to STAT5A

Item#:

sAP-0770

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0770
Product Name	Mouse Monoclonal Antibody to STAT5A
Target Molecle	STAT5A
Aliases	MGF; STAT5
Species	Human;
MW	90.6kDa
Enterez GeneID	6776
General Information	The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. ; ;
Immunogen	Purified recombinant fragment of human STAT5A (AA
Clone	MM6D4;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1.FEBS J. 2011 Sep;278(17)