Mouse Monoclonal Antibody to PTPN11

Item#:

sAP-0758

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0758
Product Name	Mouse Monoclonal Antibody to PTPN11
Target Molecle	PTPN11
Aliases	CFC; NS1; SHP2; BPTP3; PTP2C; PTP-1D; SH-PTP2; SH-PTP3; MGC14433
Species	Human;
MW	68.4kDa
Enterez GeneID	5781
General Information	The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen	Purified recombinant fragment of human PTPN11 (AA
Clone	MM6D9;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1.J Cancer Res Clin Oncol. 2011 Dec;137(12)