Mouse Monoclonal Antibody to CSNK2A2

Item#:

sAP-0755

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0755
Product Name	Mouse Monoclonal Antibody to CSNK2A2
Target Molecle	CSNK2A2
Aliases	CK2A2; CSNK2A1; FLJ43934
Species	Human; Mouse;
MW	41.2kDa
Enterez GeneID	1459
General Information	Casein kinase II (CK2) is a constitutively active, ubiquitously expressed serine/threonine protein kinase that is thought to have a regulatory function in cell proliferation, cell differentiation and apoptosis. CK2 functions as a tetrameric complex consisting of two regulatory beta-subunits and two catalytic units (alpha and alpha') in a homomeric or heteromeric conformation. Whilst the alpha- and alpha'-subunits are catalytically identical, proteins that regulate CK2, such as cdc2 and Hsp90, preferentially bind to the alpha and not the alpha'-subunit. CK2 can phosphorylate a number of key intracellular signaling proteins implicated in tumor suppression (p53 and PTEN) and tumorigenesis (myc, jun, NF-kappaB). CK2 is also thought to influence Wnt signaling via beta-catenin phosphorylation and the PI 3-K signaling pathway via the phosphorylation of Akt.
Immunogen	Purified recombinant fragment of human CSNK2A2 (AA
Clone	MM1E1;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1.J Gen Virol. 2010 Dec;91(Pt 12)