Mouse Monoclonal Antibody to VAV1

Item#:

sAP-0740

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0740
Product Name	Mouse Monoclonal Antibody to VAV1
Target Molecle	VAV1
Aliases	VAV
Species	Human
MW	98.3kDa
Enterez GeneID	7409
General Information	The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication.
Immunogen	Purified recombinant fragment of human VAV1 (AA
Clone	MM2E11;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1.J Biol Chem. 2011 Jan 21;286(3)