Mouse Monoclonal Antibody to HEXA

Item#:

sAP-0693

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0693
Product Name	Mouse Monoclonal Antibody to HEXA
Target Molecle	HEXA
Aliases	TSD
Species	Human
MW	60.7kDa
Enterez GeneID	3073
General Information	This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).
Immunogen	Purified recombinant fragment of human HEXA expressed in E. Coli. ;
Clone	MM3F10;
Isotype	Mouse IgG2b
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	J Biol Chem. 2009 Dec 25;284(52)