Mouse Monoclonal Antibody to LRP5

Item#:

sAP-0686

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0686
Product Name	Mouse Monoclonal Antibody to LRP5
Target Molecle	LRP5
Aliases	HBM; LR3; OPS; EVR1; EVR4; LRP7; OPPG; BMND1; OPTA1; VBCH2
Species	Human
MW	179kDa
Enterez GeneID	4041
General Information	This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.
Immunogen	Purified recombinant fragment of human LRP5 expressed in E. Coli. ;
Clone	MM2B11;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Clin Cardiol. 2010 Nov;33(11)