Mouse Monoclonal Antibody to UBB

Item#:

sAP-0667

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0667
Product Name	Mouse Monoclonal Antibody to UBB
Target Molecle	UBB
Aliases	UBC; UBA52; RPS27A
Species	Human
MW	26kDa
Enterez GeneID	7314
General Information	This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome.
Immunogen	Purified recombinant fragment of human UBB expressed in E. Coli. ;
Clone	MM3C12;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1.J Biol Chem. 2008 Nov 7;283(45)