Mouse Monoclonal Antibody to CYP1A1

Item#:

sAP-0662

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0662
Product Name	Mouse Monoclonal Antibody to CYP1A1
Target Molecle	CYP1A1
Aliases	AHH; AHRR; CP11; CYP1; P1-450; P450-C; P450DX
Species	Human
MW	58kDa
Enterez GeneID	1543
General Information	This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.
Immunogen	Purified recombinant fragment of human CYP1A1 expressed in E. Coli. ;
Clone	MM6G5;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Int J Cancer. 2009 May 1;124(9)