Mouse Monoclonal Antibody to SKP1

Item#:

sAP-0644

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0644
Product Name	Mouse Monoclonal Antibody to SKP1
Target Molecle	SKP1
Aliases	OCP2; p19A; EMC19; SKP1A; OCP-II; TCEB1L; MGC34403
Species	Human
MW	19kDa
Enterez GeneID	6500
General Information	This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.
Immunogen	Purified recombinant fragment of human SKP1 expressed in E. Coli. ;
Clone	MM4E11;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide. ;
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Mol Cancer Ther. 2009 Dec;8(12)