Mouse Monoclonal Antibody to NQO1

Item#:

sAP-0642

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0642
Product Name	Mouse Monoclonal Antibody to NQO1
Target Molecle	NQO1
Aliases	DTD; QR1; DHQU; DIA4; NMOR1; NMORI
Species	Human
MW	31kDa
Enterez GeneID	1728
General Information	This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Immunogen	Purified recombinant fragment of human NQO1 expressed in E. Coli. ;
Clone	MM4D12;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide. ;
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Biochem J. 2010 Mar 29;427(2)