Mouse Monoclonal Antibody to MSH6

Item#:

sAP-0633

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0633
Product Name	Mouse Monoclonal Antibody to MSH6
Target Molecle	MSH6
Aliases	GTBP; HSAP; HNPCC5
Species	Human;
MW	160kDa
Enterez GeneID	2956
General Information	This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein of this gene combines with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer.
Immunogen	Purified recombinant fragment of human MSH6 expressed in E. Coli. ;
Clone	MM5B11;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Cell Signal. 2009 Dec;21(12)