Mouse Monoclonal Antibody to DLK1

Item#:

sAP-0630

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0630
Product Name	Mouse Monoclonal Antibody to DLK1
Target Molecle	DLK1
Aliases	DLK; FA1; ZOG; pG2; PREF1; Pref-1
Species	Human;
MW	41kDa
Enterez GeneID	8788
General Information	This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass.
Immunogen	Purified recombinant fragment of human DLK1 expressed in E. Coli. ;
Clone	MM3A10;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Cancer Lett. 2009 Aug 28;281(2)