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Mouse Monoclonal Antibody to TNNI2
Item#:
sAP-0628
Size Price Quantity
50.0 ug $320.00
Catalog Number sAP-0628
Product Name Mouse Monoclonal Antibody to TNNI2
Target Molecle TNNI2
Aliases DA2B; FSSV; fsTnI; AMCD2B
Species Human
MW 21kDa
Enterez GeneID 7136
General Information This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene.
Immunogen Purified recombinant fragment of human TNNI2 expressed in E. Coli. ;
Clone MM2F12A8;
Isotype Mouse IgG1
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1. Cell. 2008 Mar 7;132(5)
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