Mouse Monoclonal Antibody to KIT

Item#:

sAP-0609

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0609
Product Name	Mouse Monoclonal Antibody to KIT
Target Molecle	KIT
Aliases	PBT; SCFR; C-Kit; CD117
Species	Human
MW	145kDa
Enterez GeneID	3815
General Information	The c-Kit proto-oncogene is a member of the receptor tyrosine kinase family and, more specifically, is closely related to the platelet derived growth factor receptor (PDGFR). c-Kit, the normal cellular homolog of the HZ4-feline sarcoma virus transforming gene (v-Kit), encodes a transmembrane receptor. c-Kit regulates a variety of biological responses including chemotaxis, cell prolif- eration, apoptosis and adhesion. c-Kit is also identical with the product of the W locus in mice and, as such, is integral to the development of mast cells and hematopoiesis. The ligand for the c-Kit receptor (KL) has been identified and is encoded at the murine steel (SI) locus. Kit is the human homolog of the proto- oncogene c-Kit. Mutations in Kit are integral for tumor growth and progression in various cancers.
Immunogen	Purified recombinant fragment of human KIT expressed in E. Coli. ;
Clone	MM1C5;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Biochem J. 2009 Dec 14;425(1)