Mouse Monoclonal Antibody to CRK

Item#:

sAP-0607

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0607
Product Name	Mouse Monoclonal Antibody to CRK
Target Molecle	CRK
Aliases	CRKII
Species	Human
MW	42kDa
Enterez GeneID	1398
General Information	This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.
Immunogen	Purified recombinant fragment of human CRK expressed in E. Coli. ;
Clone	MM3G11E8;
Isotype	Mouse IgG2b
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Seikagaku. 2009 May;81(5)