Mouse Monoclonal Antibody to LMNA

Item#:

sAP-0597

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0597
Product Name	Mouse Monoclonal Antibody to LMNA
Target Molecle	LMNA
Aliases	FPL; IDC; LFP; CDDC; EMD2; FPLD; HGPS; LDP1; LMN1; LMNC; PRO1; CDCD1; CMD1A; FPLD2; LMNL1; CMT2B1
Species	Human; Mouse; Rat
MW	74kDa
Enterez GeneID	4000
General Information	The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Through alternate splicing, this gene encodes three type A lamin isoforms. Mutations in this gene lead to several diseases
Immunogen	Purified recombinant fragment of human LMNA expressed in E. Coli.
Clone	MM4E7;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. J Biol Chem. 2010 Mar 12;285(11)