Mouse Monoclonal Antibody to AIF

Item#:

sAP-0595

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0595
Product Name	Mouse Monoclonal Antibody to AIF
Target Molecle	AIF
Aliases	AIFM1; AIF; PDCD8; COXPD6; MGC111425
Species	Human; Mouse; Monkey; Rat
MW	67kDa
Enterez GeneID	9131
General Information	This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10
Immunogen	Purified recombinant fragment of human AIF expressed in E. Coli. ;
Clone	MM4E7;
Isotype	Mouse IgG2b
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide. ;
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. J Clin Invest. 2009 May;119(5)