Mouse Monoclonal Antibody to GCK

Item#:

sAP-0593

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0593
Product Name	Mouse Monoclonal Antibody to GCK
Target Molecle	GCK
Aliases	GK; GLK; HK4; HHF3; HKIV; HXKP; LGLK; MODY2; FGQTL3
Species	Human
MW	52kDa
Enterez GeneID	2645
General Information	Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI).
Immunogen	Purified recombinant fragment of human GCK expressed in E. Coli. ;
Clone	MM4G6;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. J Biol Chem. 2009 Dec 4;284(49)