Mouse Monoclonal Antibody to XRCC5

Item#:

sAP-0587

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0587
Product Name	Mouse Monoclonal Antibody to XRCC5
Target Molecle	XRCC5
Aliases	KU80; KUB2; Ku86; NFIV; KARP1; KARP-1; FLJ39089
Species	Human; Mouse
MW	86kDa
Enterez GeneID	7520
General Information	The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Immunogen	Purified recombinant fragment of human XRCC5 expressed in E. Coli. ;
Clone	MM5C5;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Arthritis Res Ther. 2009;11(6)