Mouse Monoclonal Antibody to BLNK

Item#:

sAP-0582

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0582
Product Name	Mouse Monoclonal Antibody to BLNK
Target Molecle	BLNK
Aliases	AGM4; BASH; LY57; SLP65; BLNK-S; SLP-65; MGC111051
Species	Human; Mouse
MW	68kDa
Enterez GeneID	29760
General Information	This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen	Purified recombinant fragment of human BLNK expressed in E. Coli. ;
Clone	MM5G9;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Mol Cell Biol. 2009 Jun;29(11)