Mouse Monoclonal Antibody to ApoE

Item#:

sAP-0565

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0565
Product Name	Mouse Monoclonal Antibody to ApoE
Target Molecle	ApoE
Aliases	AD2; LPG; LDLCQ5; MGC1571
Species	Human
MW	36kDa
Enterez GeneID	348
General Information	Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Tissue specificity
Immunogen	Purified recombinant fragment of human ApoE expressed in E. Coli. ;
Clone	MM1H4;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Cell Host Microbe. 2008 Dec 11;4(6)