Mouse Monoclonal Antibody to MYC

Item#:

sAP-0559

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0559
Product Name	Mouse Monoclonal Antibody to MYC
Target Molecle	MYC
Aliases	MRTL; c-Myc; bHLHe39
Species	Human
MW	49kDa
Enterez GeneID	4609
General Information	The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. (provided by RefSeq).
Immunogen	Purified recombinant fragment of human MYC expressed in E. Coli. ;
Clone	MM7E10;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Biochem Cell Biol. 2011 Apr;89(2)