Mouse Monoclonal Antibody to EIF4E

Item#:

sAP-0540

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0540
Product Name	Mouse Monoclonal Antibody to EIF4E
Target Molecle	EIF4E
Aliases	CBP; EIF4F; EIF4E1; EIF4EL1; MGC111573; EIF4E
Species	Human
MW	25kDa
Enterez GeneID	1977
General Information	eIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types. Several kinases are currently being investigated as potential regulators of eIF4E including PKC and/or the MAP kinase activated Mnk.
Immunogen	Purified recombinant fragment of human EIF4E expressed in E. Coli. ;
Clone	MM5D11;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Ai Zheng. 2008 Mar;27(3)