Mouse Monoclonal Antibody to MSI2

Item#:

sAP-0530

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0530
Product Name	Mouse Monoclonal Antibody to MSI2
Target Molecle	MSI2
Aliases	MSI2H; MGC3245; FLJ36569; MSI2
Species	Human
MW	35kDa
Enterez GeneID	124540
General Information	Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid protein that localizes to the cytoplasm and contains two RRM (RNA recognition motif) domains. Expressed ubiquitously at low levels, Msi2 functions as an RNA binding protein that, by regulating the expression of target mRNAs, is thought to play a role in the proliferation and maintenance of stem cells within the central nervous system. Msi2 is subject to posttranslational phosphorylation and is upregulated in response to brain injury, suggesting a role in healing and brain tissue regeneration. Chromosomal aberrations involving the Msi2 gene are associated with the progression of chronic myeloid leukemia. Multiple isoforms of Msi2 exist due to alternative splicing events.Tissue specificity
Immunogen	Purified recombinant fragment of human MSI2 expressed in E. Coli.
Clone	MM2C11;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. BMC Cancer. 2008 Apr 18;8