Mouse Monoclonal Antibody to ATM

Item#:

sAP-0525

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0525
Product Name	Mouse Monoclonal Antibody to ATM
Target Molecle	ATM
Aliases	AT1; ATA; ATC; ATD; ATE; ATDC; TEL1; TELO1; MGC74674; DKFZp781A0353; ATM
Species	Human
MW	351kDa
Enterez GeneID	472
General Information	The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.Tissue specificity
Immunogen	Purified recombinant fragment of human ATM expressed in E. Coli.
Clone	MM5C5;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Oncol Rep. 2008 Dec;20(6)