Mouse Monoclonal Antibody to CRTC3

Item#:

sAP-0521

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0521
Product Name	Mouse Monoclonal Antibody to CRTC3
Target Molecle	CRTC3
Aliases	TORC3; FLJ21868; CRTC3
Species	Human; Monkey
MW	68kDa
Enterez GeneID	64784
General Information	Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR) .Tissue specificity
Immunogen	Purified recombinant fragment of human CRTC3 expressed in E. Coli.
Clone	MM5G9;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. J Biol Chem. 2009 Jan 2;284(1)