Mouse Monoclonal Antibody to MAP2K4

Item#:

sAP-0520

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0520
Product Name	Mouse Monoclonal Antibody to MAP2K4
Target Molecle	MAP2K4
Aliases	JNKK; MEK4; MKK4; SEK1; JNKK1; SERK1; MAPKK4; PRKMK4; MAP2K4
Species	Human
MW	42kDa
Enterez GeneID	6416
General Information	This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver.Tissue specificity
Immunogen	Purified recombinant fragment of human MAP2K4 expressed in E. Coli.
Clone	MM5H4;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Am J Med Genet B Neuropsychiatr Genet. 2008 Jun 5;147B(4)