Mouse Monoclonal Antibody to CTCF

Item#:

sAP-0501

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0501
Product Name	Mouse Monoclonal Antibody to CTCF
Target Molecle	CTCF
Aliases	CTCF
Species	Human; Monkey
MW	83kDa
Enterez GeneID	10664
General Information	This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors.Tissue specificity
Immunogen	Purified recombinant fragment of human CTCF expressed in E. Coli.
Clone	MM1D11;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Br J Cancer. 2008 Sep 2;99(5)